Inhibition of IP6K1 suppresses neutrophil-mediated pulmonary damage in bacterial pneumonia

Abstract

The significance of developing host-modulating personalized therapies to counteract the growing threat of antimicrobial resistance is well-recognized because such resistance cannot be overcome using microbe-centered strategies alone. Immune host defenses must be finely controlled during infection to balance pathogen clearance with unwanted inflammation… (More)
DOI: 10.1126/scitranslmed.aal4045

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6 Figures and Tables