Inhibition of Helicobacter pylori binding to gastrointestinal epithelial cells by sialic acid-containing oligosaccharides.

@article{Simn1997InhibitionOH,
  title={Inhibition of Helicobacter pylori binding to gastrointestinal epithelial cells by sialic acid-containing oligosaccharides.},
  author={Piedad Mateos Sim{\'o}n and Phill Goode and Ali E. Mobasseri and David W Zopf},
  journal={Infection and immunity},
  year={1997},
  volume={65 2},
  pages={
          750-7
        }
}
Helicobacterpylori, the ulcer pathogen residing in the human stomach, binds to epithelial cells of the gastric antrum. We have examined binding of 13 bacterial isolates to epithelial cell lines by use of a sensitive microtiter plate method in which measurement of bacterial urease activity provides the means for quantitation of bound organisms. Several established human gastrointestinal carcinoma cell lines grown as monolayers were compared for suitability in these assays, and the duodenum… CONTINUE READING

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