Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner


A peptide vaccine designed to induce T-cell immunity to telomerase, GV1001, has been shown to modulate cellular signaling pathways and confer a direct anti-cancer effect through the interaction with heat shock protein (HSP) 90 and 70. Here, we have found that GV1001 can modulate transactivation protein-mediated human immunodeficiency virus (HIV)-1… (More)
DOI: 10.1038/srep28896


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