Inhibition of-Glucosidase and-Amylase by Flavonoids

  title={Inhibition of-Glucosidase and-Amylase by Flavonoids},
  author={T Kenjiro and Tsuchida Kouta and Akamatsu and Matsumuira Tomoko and ATSUOKA},
The inhibitory activity of six groups of flavonoids against yeast and rat small intestinal cr-g]ucosidases and porcine pancreatic a-amylase was compared, and chemical structures of flavonoids responsible for the inhibitory activity were evaluated. Yeast a-glucosidase was potently inhibited by the anthocyanidin, isoflavone and flavonol groups with the TCso values less than 15 pM, The fbllowing structures enhanced the inhibitory activity: the unsaturated C ring, 3-OH, 4-CO, the Iinkage of the B… CONTINUE READING


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Inhibitory actMty of cyanidin - 3 - rutinostdc on org ] ucosidase

  • AS Yibchok
  • J EnzuTne lnhibition Med Chem
  • 2004

, 6 - Hydroxyflavonoids as cr - glucosidasc inhibitors from Marjoram ( Orieanum mojorana ) leaves

  • J Kawabata, K Mizuhata, E Sato, T Nishioka, T AoyarnaMKasai
  • Biosci Biotechnol Bjochem
  • 2003

Luteolin , a [ lavone , does not suppress postpran - dtal glucose absorption through an inhibition of crg ] u - cosidase action

  • Z Matsui, S Hayashida, K Matsumoto
  • Biosci Biotechnol Biochem
  • 2002

Alpha - gtucosidase inhibttory action of natural acytated anthocyanins . 2 , Alpha - glucosidasc inhibition by isolated acylated anthocyanins

  • K OkiTSugita, N lbrahara
  • 2001

Gcnistein , a soy isoflavone , is a potent a - glucosiduse inhibitor

  • DS Lcc
  • FEBS Lett SOI
  • 2001

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