Inhibition of G-protein signaling by dominant gain-of-function mutations in Sst2p, a pheromone desensitization factor in Saccharomyces cerevisiae.

Abstract

Genetic analysis of cell-cell signaling in Saccharomyces cerevisiae has led to the identification of a novel factor, known as Sst2p, that promotes recovery after pheromone-induced growth arrest (R. K. Chan and C. A. Otte, Mol. Cell. Biol. 2:11-20, 1982). Loss-of-function mutations lead to increased pheromone sensitivity, but this phenotype is partially… (More)

Topics

7 Figures and Tables

Cite this paper

@article{Dohlman1995InhibitionOG, title={Inhibition of G-protein signaling by dominant gain-of-function mutations in Sst2p, a pheromone desensitization factor in Saccharomyces cerevisiae.}, author={Henrik G. Dohlman and D Apaniesk and Y Chen and Junmin Song and Deborah R Nusskern}, journal={Molecular and cellular biology}, year={1995}, volume={15 7}, pages={3635-43} }