Inhibition of Fibrocyte Differentiation by Serum Amyloid P 1

  title={Inhibition of Fibrocyte Differentiation by Serum Amyloid P 1},
  author={D. Pilling and C. Buckley and M. Salmon and R. Gomer},
  journal={The Journal of Immunology},
  pages={5537 - 5546}
  • D. Pilling, C. Buckley, +1 author R. Gomer
  • Published 2003
  • Medicine, Biology
  • The Journal of Immunology
  • Wound healing and the dysregulated events leading to fibrosis both involve the proliferation and differentiation of fibroblasts and the deposition of extracellular matrix. Whether these fibroblasts are locally derived or from a circulating precursor population is unclear. Fibrocytes are a distinct population of fibroblast-like cells derived from peripheral blood monocytes that enter sites of tissue injury to promote angiogenesis and wound healing. We have found that CD14+ peripheral blood… CONTINUE READING
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