Inhibition of DNA methyltransferase by microbial inhibitors and fatty acids.

  title={Inhibition of DNA methyltransferase by microbial inhibitors and fatty acids.},
  author={K. Suzuki and K. Nagao and J. Tokunaga and N. Katayama and M. Uyeda},
  journal={Journal of enzyme inhibition},
  volume={10 4},
Streptomyces sp. strain No. 560 produces four kinds of DNA methyltransferase inhibitors in the culture filtrate. One of them, DMI-4 was distinguished from DMI-1, -2 and -3 previously reported with respect to certain properties, DMI-4 is considered to be a triglyceride consisting of the fatty acids anteisopentadecanoic acid (C15:0), isopalmitic acid (C16:0) and isostearic acid (C18:0) from the results of gas chromatography analysis. Since DMI-4 contains three molecules of fatty acid, and the… Expand
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[Metabolites produced by actinomycetes--antiviral antibiotics and enzyme inhibitors].
  • M. Uyeda
  • Chemistry, Medicine
  • Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  • 2004
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