Inhibition of Chemically Induced Mammary and Colon Tumor Promotion by Caloric Restriction in Rats Fed Increased Dietary Fat1


Tumor promotion associated with increased dietary fat may be inhib ited by reduction in total caloric intake. This hypothesis was tested in rats given either 7,12-dimethylbenz(fl)anthracene to induce mammary tumors or 1,2-dimethylhydrazine to induce colon tumors. One week after dosage with either carcinogen, the rats were fed semipurified diets that… (More)


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