Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.

Abstract

CIP2A is a recent identified oncogene that inhibits protein phosphatase 2A (PP2A) and stabilizes c-Myc in cancer cells. To investigate the potential oncogenic role and prognostic value of CIP2A, we comprehensively analyzed the CIP2A expression levels in pan-cancer and observed high expression level of CIP2A in majority cancer types, including hepatocellular… (More)
DOI: 10.1016/j.bbrc.2017.11.124

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Cite this paper

@article{Yang2018InhibitionOC, title={Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.}, author={Xue Yang and Kai Qu and Jie Tao and Guozhi Yin and Shaoshan Han and Qingguang Liu and Hao Sun}, journal={Biochemical and biophysical research communications}, year={2018}, volume={495 2}, pages={1807-1814} }