Inhibition of BMP2‐induced, TAK1 kinase‐mediated neurite outgrowth by Smad6 and Smad7

@article{Yanagisawa2001InhibitionOB,
  title={Inhibition of BMP2‐induced, TAK1 kinase‐mediated neurite outgrowth by Smad6 and Smad7},
  author={M. Yanagisawa and K. Nakashima and K. Takeda and W. Ochiai and T. Takizawa and M. Ueno and M. Takizawa and H. Shibuya and T. Taga},
  journal={Genes to Cells},
  year={2001},
  volume={6}
}
Background BMP2 is known to play a wide variety of roles, including some in the development of the nervous system. This cytokine has been reported to induce neurite outgrowth in rat pheochromocytoma PC12 cells via the activation of a p38 MAP kinase, although its regulatory mechanism remains largely to be elucidated. 
Non-Smad Signaling Pathways of the TGF-β Family.
  • Ying E. Zhang
  • Biology, Medicine
  • Cold Spring Harbor perspectives in biology
  • 2017
BMP Enhances Transcriptional Responses to NGF During PC12 Cell Differentiation
Bone morphogenetic protein signalling in NGF-stimulated PC12 cells.
Nerve growth factor mediates activation of the Smad pathway in PC12 cells.
Interplays Between The Smad and Map Kinase Signaling Pathways
Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A‐dependent MEK‐ERK1/2 signaling pathway
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