Inhibition of Adipogenesis by Thiourea Derivatives.

  title={Inhibition of Adipogenesis by Thiourea Derivatives.},
  author={Hina Siddiqui and Sarah Shafi and Farah Mukhtar and Asma Ejaz and Atta-ur-Rahman and Mohammad Iqbal Choudhary},
  journal={Medicinal chemistry (Shariqah (United Arab Emirates))},
  volume={14 5},
BACKGROUND Obesity is one of the major health problems with inherent risk of type 2 diabetes, hypertension, CVDs, etc. Adipogenesis is a major contributor in the process of obesity. Inhibition of adipocytes differentiation is one of the key approaches to treat obesity. OBJECTIVE To discover the new inhibitors of adipogenesis as the treatment for obesity. METHOD We describe here, the synthesis, and anti-adipogenic activity of thiourea derivatives 1-14. These derivatives were synthesized by… CONTINUE READING