Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells

@article{Terauchi2006InhibitionOA,
  title={Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells},
  author={Mikio Terauchi and Hiroaki Kajiyama and Kiyosumi Shibata and Kazuhiko Ino and Akihiro Nawa and Shigehiko Mizutani and Fumitaka Kikkawa},
  journal={BMC Cancer},
  year={2006},
  volume={7},
  pages={140 - 140}
}
Aminopeptidase N (APN/CD13), a 150-kDa metalloprotease, is a multifunctional cell surface aminopeptidase with ubiquitous expression. Recent studies have suggested that APN/CD13 plays an important role in tumor progression of several human malignancies. In the current study, we investigated the role of APN/CD13 in ovarian carcinoma (OVCA) progression. We first examined the expression of APN/CD13 at the protein level in a variety of OVCA cell lines and tissues. We subsequently investigated… CONTINUE READING