Inhibition of α-glucosidase by new prenylated flavonoids from euphorbia hirta L. herb.

  title={Inhibition of $\alpha$-glucosidase by new prenylated flavonoids from euphorbia hirta L. herb.},
  author={Manjur Ali Sheliya and Begum Rayhana and Abuzer Ali and Krishna Kolappa Pillai and Vidhu Aeri and Manju Sharma and Showkat Rasool Mir},
  journal={Journal of ethnopharmacology},

Isolation, Identification and Pharmacological Effects of Mandragora autumnalis Fruit Flavonoids Fraction

Since ancient times, Mandragora autumnalis has been used as a traditional medicinal plant for the treatment of numerous ailments. In light of this, the current study was designed to isolate and

Chemical Composition, α-Glucosidase Inhibitory and Anticancer Activity of Essential Oil of Thymus vulgaris Leaves

  • Abuzer Ali
  • Journal of Essential Oil Bearing Plants
  • 2021
Abstract Dietary herbs are used for imparting flavour, aroma, and piquancy to foods. Besides their role in improving food quality, spices also have health benefits, such as anticancer, antidiabetic,

Flavonoids from the Genus Euphorbia: Isolation, Structure, Pharmacological Activities and Structure–Activity Relationships

The structure–activity relationship studies showed that methylation of the hydroxyl groups on C-3 or C-7 reduces the activities while glycosylation loses the activity and that the parent skeletal structure is essential in retaining the activity, which can offer potential alternative scaffolds towards development of new Euphorbia-based therapeutic agents.

Phytopharmacognostic evaluation of plant Euphorbia hirta L.

The present study considers the detail investigation of macroscopy, microscopy, preliminary qualititative phytochemical analysis, physicochemical evaluations, chromatography and infra red spectroscopy profiling to identify the powder characters of Euphorbia hirta L.

In vitro acetylcholinesterase, tyrosinase inhibitory potentials of secondary metabolites from Euphorbia schimperiana and Euphorbia balsamifera

The AChE inhibitory effect of pure compounds exhibited promising activity, where 4-O-ethylgallic acid demonstrated 51.1%, while the highest tyrosinase inhibition was demonstrated by isoorientin with 50.6% compared to the reference drug (60%).

Phytochemicals of Euphorbia hirta L. and Their Inhibitory Potential Against SARS-CoV-2 Main Protease

Phytochemical components of E. hirta were investigated in silico for their potential to inhibit the severe acute respiratory syndrome-coronavirus-2 main protease (SARS-CoV-2 Mpro), a coronavirus disease 2019 (COVID-19) drug target that plays a critical role in the infection process of SARS- CoV- 2.

In-vitro Antidiabetic on leaf extracts of Mimosa pudica and Euphorbia hirta - A Comparative Study

In the present study, it was revealed that the medicinal plant Euphorbia hirta showed a better antidiabetic activity than Mimosa pudica.

Changes in α-glucosidase inhibition, antioxidant, and phytochemical profiles during the growth of Tartary buckwheat (Fagopyrum tataricum Gaertn)

ABSTRACT Tartary buckwheat has become popular healthful food due to its antidiabetic and antioxidant activities. In the current study, the in-vitro α-glucosidase inhibitory and antioxidative

New diterpenoids from the stems of Euphorbia antiquorum growing in Vietnam

Phytochemical analysis of Euphorbia antiquorum stem extracts afforded two new ent-atisane compounds, ent-3α-acetoxy-16β,17,18-trihydroxyatisane and ent- 3α,14,16 β,17-tetrahydroxyatisanes, which were elucidated by spectroscopic data analysis and comparison with published NMR data.



Antidiabetic and antioxidant potentials of Euphorbia hirta leaves extract studied in streptozotocin-induced experimental diabetes in rats.

The antidiabetic and antioxidant potentials of E. hirta leaves in streptozotocin-induced experimental diabetes in rats were evaluated and the hypoglycemic activity of the leaves extract was comparable with gliclazide, a standard reference drug.

Anti-inflammatory Active Compounds from the n-Hexane Extract of Euphorbia hirta

The n-hexane extract of the aerial parts of Euphorbia hirta L. (Euphorbiaceae) and its main triterpenes, β-amyrin (1), 24-methy- lencycloartenol (2), and β-sitosterol (3) were evaluated for anti-

Comparative evaluation of quercetin, isoquercetin and rutin as inhibitors of alpha-glucosidase.

The results indicated that Que, Iso and Rut could bind alpha-glucosidase to form a new complex, which exhibited a strong static fluorescence quenching via nonradiation energy transfer, and an obvious blue shift of maximum fluorescence, which would be significant for the development of more powerful antidiabetes drugs and efficacious utilization of tartary buckwheat.

Glycosidase inhibitory flavonoids from Sophora flavescens.

Results showed that 8-lavandulyl group in B-ring was a key factor of the glycosidase inhibitory activities, and the inhibition pattern was noncompetitive for alpha-glucosidase, whereas mixed inhibition was observed for beta-amylase.

Phenols and flavonoids from the aerial part of Euphorbia hirta.

Quantitative Estimation of an Antidiarrhoeic Marker in Euphorbia hirta Samples

The effect of various controlling parameters was studied and it was found that the varying proportions of plant parts in the samples of E. hirta is responsible for variation in active marker concentration.

Antidiabetic and Free Radicals Scavenging Potential of Euphorbia hirta Flower Extract

The present study was carried out to evaluate antidiabetic and in vitro free radicals scavenging effects of flower extract of Euphorbia hirta and all the extracts showed antioxidant activity in all the tested methods.