Inhibition of α-glucosidase by new prenylated flavonoids from euphorbia hirta L. herb.

@article{Sheliya2015InhibitionO,
  title={Inhibition of $\alpha$-glucosidase by new prenylated flavonoids from euphorbia hirta L. herb.},
  author={Manjur Ali Sheliya and Begum Rayhana and Abuzer Ali and Krishna Kolappa Pillai and Vidhu Aeri and Manju Sharma and Showkat Rasool Mir},
  journal={Journal of ethnopharmacology},
  year={2015},
  volume={176},
  pages={
          1-8
        }
}
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40 Citations

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References

SHOWING 1-10 OF 35 REFERENCES

Vitexin and isovitexin from the Leaves of Ficus deltoidea with in-vivo α-glucosidase inhibition.

Antidiabetic and antioxidant potentials of Euphorbia hirta leaves extract studied in streptozotocin-induced experimental diabetes in rats.

The antidiabetic and antioxidant potentials of E. hirta leaves in streptozotocin-induced experimental diabetes in rats were evaluated and the hypoglycemic activity of the leaves extract was comparable with gliclazide, a standard reference drug.

Anti-inflammatory Active Compounds from the n-Hexane Extract of Euphorbia hirta

The n-hexane extract of the aerial parts of Euphorbia hirta L. (Euphorbiaceae) and its main triterpenes, β-amyrin (1), 24-methy- lencycloartenol (2), and β-sitosterol (3) were evaluated for anti-…

Inhibitory potential of trilobatin from Lithocarpus polystachyus Rehd against α-glucosidase and α-amylase linked to type 2 diabetes

Comparative evaluation of quercetin, isoquercetin and rutin as inhibitors of alpha-glucosidase.

The results indicated that Que, Iso and Rut could bind alpha-glucosidase to form a new complex, which exhibited a strong static fluorescence quenching via nonradiation energy transfer, and an obvious blue shift of maximum fluorescence, which would be significant for the development of more powerful antidiabetes drugs and efficacious utilization of tartary buckwheat.

Glycosidase inhibitory flavonoids from Sophora flavescens.

Results showed that 8-lavandulyl group in B-ring was a key factor of the glycosidase inhibitory activities, and the inhibition pattern was noncompetitive for alpha-glucosidase, whereas mixed inhibition was observed for beta-amylase.

Phenols and flavonoids from the aerial part of Euphorbia hirta.

Quantitative Estimation of an Antidiarrhoeic Marker in Euphorbia hirta Samples

The effect of various controlling parameters was studied and it was found that the varying proportions of plant parts in the samples of E. hirta is responsible for variation in active marker concentration.

Antidiabetic and Free Radicals Scavenging Potential of Euphorbia hirta Flower Extract

The present study was carried out to evaluate antidiabetic and in vitro free radicals scavenging effects of flower extract of Euphorbia hirta and all the extracts showed antioxidant activity in all the tested methods.

Prenylated flavonoids from Artocarpus altilis: antioxidant activities and inhibitory effects on melanin production.