Inhibition in vitro of the replication of murine cytomegalovirus or reovirus type 3 by the glutamine analogue acivicin

Abstract

The replication of synchronised cultures of Balb/c L-3T3 fibroblasts was shown to require glutamine at a concentration of at least 0.12 mM, but the replication of murine cytomegalovirus (MCMV) or reovirus type 3 in the cells required at least 0.25 mM glutamine. In the presence of 2 mM glutamine, the glutamine analogue acivicin inhibited DNA synthesis at a… (More)
DOI: 10.1007/BF01309805

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