Inhibition by yeast killer toxin-like antibodies of oral Streptococci adhesion to tooth surfaces in an ex vivo model.

@article{Conti2002InhibitionBY,
  title={Inhibition by yeast killer toxin-like antibodies of oral Streptococci adhesion to tooth surfaces in an ex vivo model.},
  author={Stefania Conti and Walter Magliani and Simona Arseni and Raffaele Frazzi and Antonella Salati and Lara Ravanetti and Luciano Polonelli},
  journal={Molecular medicine},
  year={2002},
  volume={8 6},
  pages={
          313-7
        }
}
BACKGROUND Monoclonal (KTmAb) and recombinant (KTscFv) anti-idiotypic antibodies, representing the internal image of a yeast killer toxin, proved to be microbicidal in vitro against important eukaryotic and prokaryotic pathogens such as Candida albicans, Pneumocystis carinii, Mycobacterium tuberculosis, Staphylococcus aureus, S. haemolyticus, Enterococcus faecalis, E. faecium, and Streptococcus pneumoniae, including multidrug-resistant strains. KTmAb and KTscFv exerted a strong therapeutic… CONTINUE READING