Inhibition by p-bromophenacyl bromide of microtubule assembly in vitro.

Abstract

Introduction Microtubules (MTs) play a central role in a variety of cellular phenomena including cell division, cell morphology and intracellular transport [ 11. Pharmacological studies of MT function and assembly involve the use of a range of MT poisons. Such agents can disrupt the control of MT dynamics either by stabilizing, e.g. taxol [2, 31, or… (More)

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