Inhibition by diethylstilboestrol of proliferative potential of follicles of different sizes in immature rat ovaries.

@article{Chakravorty1991InhibitionBD,
  title={Inhibition by diethylstilboestrol of proliferative potential of follicles of different sizes in immature rat ovaries.},
  author={A K Chakravorty and Virendra B. Mahesh and Thomas M. Mills},
  journal={Journal of reproduction and fertility},
  year={1991},
  volume={92 2},
  pages={323-32}
}
Intact immature female rats were treated with 1, 2, 3 or 4 subcutaneous injections of 2 mg diethylstilboestrol (DES)/rat at intervals of 24 h and then killed. Ovaries were collected, cleaned, enzymically digested and serially filtered through Teflon sieves to yield follicles of diameter less than 200 microns (small), 200-400 microns (medium) and greater… CONTINUE READING