Inhibition by dietary tea polyphenols of chemical mediator release from rat peritoneal exudate cells.

@article{Matsuo2000InhibitionBD,
  title={Inhibition by dietary tea polyphenols of chemical mediator release from rat peritoneal exudate cells.},
  author={Naoki Matsuo and Koji Yamada and Mitsuo Mori and Kentaro Shoji and Takashi Ueyama and Shunji Yunoki and Kyoko Yamashita and Megumi Ozeki and Michihiro Sugano},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2000},
  volume={64 7},
  pages={1437-43}
}
Male Wistar rats were given purified diets containing safflower (SAF), perilla (PER), or palm (PAL) oils with or without 1% tea polyphenols (TP) for 3 weeks, and chemical mediator releasing activity from rat peritoneal exudate cells (PEC) was measured. Histamine releasing activity was not influenced by TP, while histamine release and intracellular histamine content were significantly increased in the PAL-fed group. On the contrary, leukotriene B4 (LTB4) release was significantly lower in rats… CONTINUE READING