Inhibition by cytoplasmic nucleotides of a new cation channel in freshly isolated human and rat type II pneumocytes.

Abstract

Here we report a 26- to 29-pS cation channel abundantly expressed in freshly isolated and primary cultured type II cells from rat or healthy human lungs. The channel was never spontaneously active in cell-attached patches but could be activated by cell permeabilization with beta-escin. Excised patch-clamp experiments revealed activation by Ca(2… (More)

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@article{Mair2004InhibitionBC, title={Inhibition by cytoplasmic nucleotides of a new cation channel in freshly isolated human and rat type II pneumocytes.}, author={Norbert Mair and Manfred Frick and Cristina Bertocchi and Thomas Haller and Albert Amberger and H Markus Weiss and Raimund Margreiter and Werner Streif and Paul Dietl}, journal={American journal of physiology. Lung cellular and molecular physiology}, year={2004}, volume={287 6}, pages={L1284-92} }