Inhibition by Theanine of Binding of [3H]AMPA, [3H]Kainate, and [3H]MDL 105,519 to Glutamate Receptors
@article{Kakuda2002InhibitionBT, title={Inhibition by Theanine of Binding of [3H]AMPA, [3H]Kainate, and [3H]MDL 105,519 to Glutamate Receptors}, author={T. Kakuda and A. Nozawa and A. Sugimoto and H. Niino}, journal={Bioscience, Biotechnology, and Biochemistry}, year={2002}, volume={66}, pages={2683 - 2686} }
In an investigation of the mechanisms of the neuroprotective effects of theanine (γ-glutamylethylamide) in brain ischemia, inhibition by theanine of the binding of [3H](RS)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA), [3H]kainate, and [3H](E)-3-(2-phenyl-2-carboxyethenyl)-4,6-dichloro-1-H-indole-2-carboxylic acid (MDL 105,519) to glutamate receptors was studied in terms of its possible inhibiting effects on the three receptor subtypes (AMPA, kainate, and NMDA glycine), with rat… CONTINUE READING
Topics from this paper
103 Citations
Theanine, an ingredient of green tea, inhibits [3H]glutamine transport in neurons and astroglia in rat brain
- Chemistry, Medicine
- Journal of neuroscience research
- 2008
- 54
Characterization of l-Theanine Excitatory Actions on Hippocampal Neurons: Toward the Generation of Novel N-Methyl-d-aspartate Receptor Modulators Based on Its Backbone.
- Medicine, Biology
- ACS chemical neuroscience
- 2017
- 5
- PDF
Role of endocannabinoid and glutamatergic systems in DOI-induced head-twitch response in mice
- Chemistry, Medicine
- Pharmacology Biochemistry and Behavior
- 2011
- 18
The effect of L-theanine and S-ketamine on d-serine cellular uptake.
- Chemistry, Medicine
- Biochimica et biophysica acta. Proteins and proteomics
- 2020
Effects of theanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission
- Chemistry, Medicine
- Nutritional neuroscience
- 2005
- 54
- Highly Influenced
L-theanine, a Component of Green Tea Prevents 3-Nitropropionic Acid (3-NP)-Induced Striatal Toxicity by Modulating Nitric Oxide Pathway
- Chemistry, Medicine
- Molecular Neurobiology
- 2016
- 18
Theanine, γ-glutamylethylamide, a unique amino acid in tea leaves, modulates neurotransmitter concentrations in the brain striatum interstitium in conscious rats
- Chemistry, Medicine
- Amino Acids
- 2007
- 50
- Highly Influenced
- PDF
The Neuropharmacology of L-Theanine(N-Ethyl-L-Glutamine)
- Chemistry, Medicine
- Journal of herbal pharmacotherapy
- 2006
- 80
The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent.
- Chemistry
- 2006
- 98
Behavioral and molecular evidence for psychotropic effects in l-theanine
- Medicine, Psychology
- Psychopharmacology
- 2011
- 33
- Highly Influenced
References
SHOWING 1-10 OF 22 REFERENCES
[3H]AMPA binding to glutamate receptor subpopulations in rat brain
- Chemistry, Medicine
- Brain Research
- 1987
- 131
Binding of the radiolabeled glycine site antagonist [3H]MDL 105,519 to homomeric NMDA-NR1a receptors.
- Chemistry, Medicine
- European journal of pharmacology
- 1996
- 28
The Binding of [3H]AMPA, a Structural Analogue of Glutamic Acid, to Rat Brain Membranes
- Chemistry, Medicine
- Journal of neurochemistry
- 1982
- 207
Specific binding of [3H]kainic acid to receptor sites in rat brain.
- Chemistry, Medicine
- Molecular pharmacology
- 1979
- 267
The GluR2 (GluR-B) hypothesis: Ca2+-permeable AMPA receptors in neurological disorders
- Biology, Medicine
- Trends in Neurosciences
- 1997
- 522
Effect of Theanine, r-Glutamylethylamide, on Brain Monoamines and Striatal Dopamine Release in Conscious Rats
- Chemistry, Medicine
- Neurochemical Research
- 2004
- 146
Postischemic Blockade of AMPA but Not NMDA Receptors Mitigates Neuronal Damage in the Rat Brain following Transient Severe Cerebral Ischemia
- Chemistry, Medicine
- Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
- 1992
- 306
- PDF
Protective effect of γ-glutamylethylamide (theanine) on ischemic delayed neuronal death in gerbils
- Medicine
- Neuroscience Letters
- 2000
- 80