Inhibition by 1'-acetoxychavicol acetate of lipopolysaccharide- and interferon-gamma-induced nitric oxide production through suppression of inducible nitric oxide synthase gene expression in RAW264 cells.

@article{Ohata1998InhibitionB1,
  title={Inhibition by 1'-acetoxychavicol acetate of lipopolysaccharide- and interferon-gamma-induced nitric oxide production through suppression of inducible nitric oxide synthase gene expression in RAW264 cells.},
  author={Takeji Ohata and Kuniaki Fukuda and Akira Murakami and Hajime Ohigashi and Takashi Sugimura and Koichi Wakabayashi},
  journal={Carcinogenesis},
  year={1998},
  volume={19 6},
  pages={1007-12}
}
Although nitric oxide (NO) is an important biological mediator, excessive production in inflammation is thought to be a causative factor of cellular injury and cancer in the long term. In the present study the effects of 1'-acetoxychavicol acetate (ACA), which has anticarcinogenic properties, on NO production in murine macrophage cell line RAW264 cells… CONTINUE READING