Inhibiting effects of theanine on caffeine stimulation evaluated by EEG in the rat.

@article{Kakuda2000InhibitingEO,
  title={Inhibiting effects of theanine on caffeine stimulation evaluated by EEG in the rat.},
  author={Takami Kakuda and Ayumu Nozawa and Tomonori Unno and Naoe Okamura and Osamu Okai},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2000},
  volume={64 2},
  pages={
          287-93
        }
}
In this study, the inhibiting action of theanine on the excitation by caffeine at the concentration regularly associated with drinking tea was investigated using electroencephalography (EEG) in rats. First, the stimulatory action by caffeine i.v. administration at a level higher than 5 micromol/kg (0.970 mg/kg) b.w. was shown by means of brain wave analysis, and this level was suggested as the minimum dose of caffeine as a stimulant. Next, the stimulatory effects of caffeine were inhibited by… CONTINUE READING
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