Inhibiting effects of cancer sera on in vitro responses of peripheral blood lymphocytes to recombinant interleukin-2.

  • F. Komatsu
  • Published 1989 in
    The Bulletin of Tokyo Medical and Dental…
The effects of cancer sera on the in vitro induction of lymphokine activated killer (LAK) cells and the killer activity of the LAK cells were determined. When the peripheral blood lymphocytes (PBLs) were incubated with recombinant interleukin-2 in a medium (RPMI 1640 + 10% normal human AB serum) for 96 hours, 53-55% of the LAK activity were induced. LAK… CONTINUE READING