Inhibin as a marker for granulosa-cell tumors.

  title={Inhibin as a marker for granulosa-cell tumors.},
  author={R E Lapp{\"o}hn and H. G. Burger and J. J. S. H. J. W. Bouma and M L Bangah and Mindert Krans and Henk de Bruijn},
  journal={The New England journal of medicine},
  volume={321 12},
Inhibin is a peptide hormone normally produced by ovarian granulosa cells. It reaches a peak of 772 +/- 38 U per liter in the follicular phase of the menstrual cycle and is undetectable in the serum of menopausal women. To determine whether measurements of serum inhibin levels would provide a biochemical marker of the presence or progression of ovarian granulosa-cell tumors and their metastases, we measured the serum immunoreactive inhibin concentrations in six women with such tumors. Three… CONTINUE READING

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