Inhibin B in males with gonadotropin-releasing hormone (GnRH) deficiency: changes in serum concentration after shortterm physiologic GnRH replacement--a clinical research center study.

@article{Seminara1996InhibinBI,
  title={Inhibin B in males with gonadotropin-releasing hormone (GnRH) deficiency: changes in serum concentration after shortterm physiologic GnRH replacement--a clinical research center study.},
  author={Stephanie Beth Seminara and Paul A Boepple and Lisa B. Nachtigall and François Pierre Pralong and Rizan Khoury and Patrick M. Sluss and A E Lecain and William Francis Crowley},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1996},
  volume={81 10},
  pages={3692-6}
}
To examine the role of inhibin B in the feedback regulation of FSH secretion in the human male, we determined serial levels in 18 men with idiopathic hypogonadotropic hypogonadism (IHH) during their initial 8 weeks of GnRH replacement. Pulsatile GnRH was administered every 2 h, with the dose increased at 2-week intervals (5-50 ng/kg/bolus). Every 2 weeks… CONTINUE READING