Inhibin B in male reproduction: pathophysiology and clinical relevance.

  title={Inhibin B in male reproduction: pathophysiology and clinical relevance.},
  author={Sarah Jayne Meachem and Eberhard Nieschlag and Manuela Simoni},
  journal={European journal of endocrinology},
  volume={145 5},
The recent availability of specific inhibin assays has demonstrated that inhibin B is the relevant circulating inhibin form in the human male. Inhibin B is a dimer of an alpha and a betaB subunit. It is produced exclusively by the testis, predominantly by the Sertoli cells in the prepubertal testis, while the site of production in the adult is still controversial. Inhibin B controls FSH secretion via a negative feedback mechanism. In the adult, inhibin B production depends both on FSH and on… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 62 extracted citations


Publications referenced by this paper.
Showing 1-10 of 95 references

Differential patterns of inhibin secretion in response to gonadotrophins stimulation in normal men

  • D Kinniburgh, RA Andersen
  • International Journal of Andrology
  • 2001

Physiological secretion of gonadotropins and inhibin B during the ®rs year of postnatal life in both sexes

  • S Borgato, R Giacchero, P Morpurgo, L Persani, P. Beck-Peccoz
  • 5th European Congress of Endocrinology,
  • 2001

Similar Papers

Loading similar papers…