Inherited variations in drug-metabolizing enzymes: significance in clinical oncology.

@article{Iyer1999InheritedVI,
  title={Inherited variations in drug-metabolizing enzymes: significance in clinical oncology.},
  author={Lalitha G Iyer},
  journal={Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology},
  year={1999},
  volume={4 4},
  pages={327-33}
}
  • Lalitha G Iyer
  • Published 1999 in
    Molecular diagnosis : a journal devoted to the…
Pharmacogenetics has emerged as a novel and challenging area of interest in oncology. Cancer chemotherapy is characterized by major intersubject variability in tumor responses and host toxicity. This variation may be caused by genetic differences in the enzymes involved in the metabolism of anticancer agents. Anticancer agents, such as 6-mercaptopurine, 5… CONTINUE READING