Inherited epigenetic variation — revisiting soft inheritance

  title={Inherited epigenetic variation — revisiting soft inheritance},
  author={Eric J. Richards},
  journal={Nature Reviews Genetics},
  • E. Richards
  • Published 1 May 2006
  • Biology
  • Nature Reviews Genetics
Phenotypic variation is traditionally parsed into components that are directed by genetic and environmental variation. The line between these two components is blurred by inherited epigenetic variation, which is potentially sensitive to environmental inputs. Chromatin and DNA methylation-based mechanisms mediate a semi-independent epigenetic inheritance system at the interface between genetic control and the environment. Should the existence of inherited epigenetic variation alter our thinking… 
Epigenetic Variations in Heredity and Evolution
  • E. Jablonka
  • Biology
    Clinical pharmacology and therapeutics
  • 2012
The biological and medical importance of epigenetics is now taken for granted, but the significance of one aspect of it—epigenetic inheritance—is less widely recognized. New data suggest that not
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