Inherited disorders of HDL metabolism and atherosclerosis.

  title={Inherited disorders of HDL metabolism and atherosclerosis.},
  author={G. K. Hovingh and Eric de Groot and Wim A van der Steeg and S. Matthijs Boekholdt and Barbara A. Hutten and Jan A. Kuivenhoven and John J. P. Kastelein},
  journal={Current opinion in lipidology},
  volume={16 2},
PURPOSE OF REVIEW Genetic disorders of HDL metabolism are rare and, as a result, the assessment of atherosclerosis risk in individuals suffering from these disorders has been difficult. Ultrasound imaging of carotid arteries has provided a tool to assess the risk in hereditary hypo and hyperalphalipoproteinemia. This review gives a comprehensive summary. RECENT FINDINGS Epidemiological studies have unequivocally shown that HDL cholesterol levels are inversely related to coronary artery… CONTINUE READING