Inherited deficiencies of the late-acting complement components other than C9 found among healthy blood donors.

@article{Inai1989InheritedDO,
  title={Inherited deficiencies of the late-acting complement components other than C9 found among healthy blood donors.},
  author={Shinya Inai and Y Akagaki and T Moriyama and Yasuo Fukumori and Kimio Yoshimura and Shiro Ohnoki and Hideyo Yamaguchi},
  journal={International archives of allergy and applied immunology},
  year={1989},
  volume={90 3},
  pages={274-9}
}
Among sera from 145,640 healthy blood donors in Osaka, 16 were found to have abnormalities in late-acting complement components other than C9. It was found that of these 16 sera, 2 were deficient in C5, 4 in C6, 6 in C7 and 4 in C8 alpha-gamma-subunit. The incidence of deficiency of each component among the Osaka blood donors was calculated as follows: C5 deficiency, 0.0014%; C6 deficiency, 0.0027%; C7 deficiency, 0.0041%; C8 alpha-gamma-subunit deficiency, 0.0027%. We confirmed that 13 donors… CONTINUE READING