Inheritance of urinary calculi in the Dalmatian.

  title={Inheritance of urinary calculi in the Dalmatian.},
  author={D. Bannasch and G. V. Ling and J. Bea and T. Famula},
  journal={Journal of veterinary internal medicine},
  volume={18 4},
  • D. Bannasch, G. V. Ling, +1 author T. Famula
  • Published 2004
  • Medicine
  • Journal of veterinary internal medicine
  • Dalmatians are unique among dogs in that they excrete uric acid in their urine as the end product of purine metabolism rather than allantoin as do other breeds of dogs. [...] Key Method We used a survey to ascertain the urinary calculi status based on clinical signs of adult Dalmatians aged 6 years or older, and we used pedigrees from these same animals to estimate the heritability of the clinical manifestation of urate calculi within the breed to be .87 (.75-.96). The prevalence of the disease was 34% (24.99…Expand Abstract
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    Genetic predisposition to purine uroliths in Dalmatian dogs.
    • R. H. Schaible
    • Medicine
    • The Veterinary clinics of North America. Small animal practice
    • 1986
    • 27
    Urolithiasis in Dalmations: 275 cases (1981-1990).
    • 17
    Defect of uric acid uptake in Dalmatian dog liver
    • 25
    Genetics and Analysis of Quantitative Traits
    • 2,344
    Regressive logistic models for familial disease and other binary traits.
    • 360
    Introduction to Quantitative Genetics
    • 8,877
    Stochastic Relaxation, Gibbs Distributions, and the Bayesian Restoration of Images
    • S. Geman, D. Geman
    • Mathematics, Medicine
    • IEEE Transactions on Pattern Analysis and Machine Intelligence
    • 1984
    • 13,422
    • PDF