Inheritance of urinary calculi in the Dalmatian.
@article{Bannasch2004InheritanceOU, title={Inheritance of urinary calculi in the Dalmatian.}, author={D. Bannasch and G. V. Ling and J. Bea and T. Famula}, journal={Journal of veterinary internal medicine}, year={2004}, volume={18 4}, pages={ 483-7 } }
Dalmatians are unique among dogs in that they excrete uric acid in their urine as the end product of purine metabolism rather than allantoin as do other breeds of dogs. [...] Key Method We used a survey to ascertain the urinary calculi status based on clinical signs of adult Dalmatians aged 6 years or older, and we used pedigrees from these same animals to estimate the heritability of the clinical manifestation of urate calculi within the breed to be .87 (.75-.96). The prevalence of the disease was 34% (24.99…Expand Abstract
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References
SHOWING 1-10 OF 21 REFERENCES
Genetic predisposition to purine uroliths in Dalmatian dogs.
- Medicine
- The Veterinary clinics of North America. Small animal practice
- 1986
- 27
Urolithiasis in Dalmations: 275 cases (1981-1990).
- Medicine
- Journal of the American Veterinary Medical Association
- 1993
- 17
Urolithiasis in dogs. II: Breed prevalence, and interrelations of breed, sex, age, and mineral composition.
- Biology, Medicine
- American journal of veterinary research
- 1998
- 44
Study of the genetic transmission of hypercholesterolemia and hypertriglyceridemia in a 195 member kindred
- Biology, Medicine
- Annals of human genetics
- 1975
- 108
Regressive logistic models for familial disease and other binary traits.
- Biology, Medicine
- Biometrics
- 1986
- 360
Stochastic Relaxation, Gibbs Distributions, and the Bayesian Restoration of Images
- Mathematics, Medicine
- IEEE Transactions on Pattern Analysis and Machine Intelligence
- 1984
- 13,422
- PDF