Inheritance of recurrent exertional rhabdomyolysis in thoroughbreds.

  title={Inheritance of recurrent exertional rhabdomyolysis in thoroughbreds.},
  author={Patricia K Dranchak and Stephanie J Valberg and Gary W Onan and Esther M. Gallant and Jennifer M Macleay and Erica C. McKenzie and Fl{\'a}vio Desessards De La C{\^o}rte and Kari J Ekenstedt and James R. Mickelson},
  journal={Journal of the American Veterinary Medical Association},
  volume={227 5},
OBJECTIVE To develop a diagnostic test for recurrent exertional rhabdomyolysis (RER) in Thoroughbreds that relied on in vitro contracture of muscle biopsy specimens and determine whether the inheritance pattern of RER diagnosed on the basis of this contracture test was consistent with an autosomal dominant trait. DESIGN Clinical trial. ANIMALS 8 adult horses with RER and 16 control adult horses for development of the contracture test; 23 foals for inheritance of RER. PROCEDURE External… CONTINUE READING


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