Inheritance mode of multiple sclerosis: the effect of HLA class II alleles is stronger than additive

Abstract

We previously identified on chromosome 6 an interval of 51 kb as the most likely interval in the HLA region for a disease-susceptibility locus for multiple sclerosis (MS). The interval was located between markers G511525 and D6S1666 and identified by the haplotype sharing statistic (HSS). The study comprised 124 patients with ancestry within the… (More)
DOI: 10.1007/s00439-004-1169-8

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