Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats.

@article{Kawamura2010InhaledHG,
  title={Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats.},
  author={Tomohiro Kawamura and Chien-Sheng Huang and Naobumi Tochigi and Sungsoo Lee and Norihisa Shigemura and Timothy R Billiar and Meinoshin Okumura and Atsunori Nakao and Yoshiya Toyoda},
  journal={Transplantation},
  year={2010},
  volume={90 12},
  pages={1344-51}
}
BACKGROUND Successful abrogation of ischemia/reperfusion (I/R) injury of lung grafts could significantly improve short- and long-term outcomes for lung transplant (LTx) recipients. Hydrogen gas has potent antioxidant and antiapoptotic properties and has been recently used in number of experimental and clinical studies. The purpose of this research was to investigate whether inhaled hydrogen gas could reduce graft I/R injury during lung transplantation. METHODS Orthotopic left LTxs were… CONTINUE READING