Inhaled formoterol dry powder versus ipratropium bromide in chronic obstructive pulmonary disease.

@article{Dahl2001InhaledFD,
  title={Inhaled formoterol dry powder versus ipratropium bromide in chronic obstructive pulmonary disease.},
  author={Ronald Dahl and Louis A P M Greefhorst and Dariusz Nowak and Vladimir Nonikov and Anne Marie Byrne and Moira H Thomson and Denise Till and Giovanni Della Cioppa},
  journal={American journal of respiratory and critical care medicine},
  year={2001},
  volume={164 5},
  pages={778-84}
}
We compared the effectiveness of inhaled formoterol with that of ipratropium in the treatment of chronic obstructive pulmonary disease (COPD). After a 2-wk run-in period, 780 patients with COPD were randomized to receive for 12 wk formoterol dry powder 12 or 24 microg twice daily, ipratropium bromide 40 microg four times daily, or placebo in a multicenter, double-blind, parallel-group study. The primary efficacy variable was the area under the curve for forced expiratory volume in 1 s (FEV(1… CONTINUE READING

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