Inhaled corticosteroid dose response using domiciliary exhaled nitric oxide in persistent asthma: the FENOtype trial.

@article{Anderson2012InhaledCD,
  title={Inhaled corticosteroid dose response using domiciliary exhaled nitric oxide in persistent asthma: the FENOtype trial.},
  author={William J. Anderson and Philip M. Short and Peter Andrew Williamson and Brian J Lipworth},
  journal={Chest},
  year={2012},
  volume={142 6},
  pages={
          1553-1561
        }
}
BACKGROUND International guidelines advocate a standard approach to asthma management for all, despite its heterogeneity. "Personalized" treatment of inflammatory asthma phenotypes confers superior benefits. We wished to evaluate dose response to inhaled corticosteroids (ICSs) in patients with asthma with an elevated fractional exhaled nitric oxide (Feno) phenotype using domiciliary measurements. METHODS We performed a randomized, crossover trial in 21 patients with mild to moderate… CONTINUE READING
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