Inhaled carbon monoxide inhibits intimal hyperplasia and provides added benefit with nitric oxide.

@article{Raman2006InhaledCM,
  title={Inhaled carbon monoxide inhibits intimal hyperplasia and provides added benefit with nitric oxide.},
  author={Kathleen G. Raman and Joel E. Barbato and Emeka Ifedigbo and Brett A. Ozanich and Mazen S. Zenati and Leo E Otterbein and Edith Tzeng},
  journal={Journal of vascular surgery},
  year={2006},
  volume={44 1},
  pages={
          151-8
        }
}
OBJECTIVE Carbon monoxide (CO) and nitric oxide (NO) have both been shown to possess vasoprotective properties. NO has successfully inhibited intimal hyperplasia in both small-animal and large-animal experimental models, whereas CO has only been studied in rodents. Evidence suggests that these two molecules may exert their vascular effects through common as well as unique signaling pathways. The purpose of this study was to determine the effect of a low concentration of inhaled CO on intimal… CONTINUE READING