Inhaled antibiotics for lower airway infections.

  title={Inhaled antibiotics for lower airway infections.},
  author={Bradley S Quon and Christopher H Goss and Bonnie W Ramsey},
  journal={Annals of the American Thoracic Society},
  volume={11 3},
Inhaled antibiotics have been used to treat chronic airway infections since the 1940s. The earliest experience with inhaled antibiotics involved aerosolizing antibiotics designed for parenteral administration. These formulations caused significant bronchial irritation due to added preservatives and nonphysiologic chemical composition. A major therapeutic advance took place in 1997, when tobramycin designed for inhalation was approved by the U.S. Food and Drug Administration (FDA) for use in… CONTINUE READING
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