Inhaled Nitric Oxide Does Not Reduce Mortality in Patients With Acute Respiratory Distress Syndrome Regardless of Severity: Systematic Review and Meta-Analysis*

@article{Adhikari2014InhaledNO,
  title={Inhaled Nitric Oxide Does Not Reduce Mortality in Patients With Acute Respiratory Distress Syndrome Regardless of Severity: Systematic Review and Meta-Analysis*},
  author={N. Adhikari and R. Dellinger and S. Lundin and D. Payen and B. Vallet and H. Gerlach and K. Park and S. Mehta and Arthur S Slutsky and J. Friedrich},
  journal={Critical Care Medicine},
  year={2014},
  volume={42},
  pages={404–412}
}
Objective:Treatment with inhaled nitric oxide improves oxygenation but not survival in mechanically ventilated patients with acute respiratory distress syndrome, but the effect may depend on the severity of hypoxemia. Our objective was to determine whether nitric oxide reduces hospital mortality in patients with severe acute respiratory distress syndrome (PaO2/FIO2 ⩽ 100 mm Hg) but not in patients with mild-moderate acute respiratory distress syndrome (100 < PaO2/FIO2 ⩽ 300 mm Hg) at the time… Expand
125 Citations
Association of Response to Inhaled Nitric Oxide and Duration of Mechanical Ventilation in Pediatric Acute Respiratory Distress Syndrome*
  • J. Dowell, N. Thomas, Nadir Yehya
  • Medicine
  • Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
  • 2017
  • 13
Role of Inhaled Nitric Oxide in the Management of Severe Acute Respiratory Distress Syndrome
  • 12
Inhaled nitric oxide in adult patients with acute respiratory distress syndrome.
  • 6
  • PDF
Inhaled Nitric Oxide Use in Pediatric Hypoxemic Respiratory Failure*
  • J. Berger, Aline B. Maddux, +15 authors D. Wessel
  • Medicine
  • Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
  • 2020
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 115 REFERENCES
Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis
  • 442
  • PDF
...
1
2
3
4
5
...