Inhalation of the essential oil of Piper guineense from Cameroon shows sedative and anxiolytic-like effects in mice.

@article{Tankam2013InhalationOT,
  title={Inhalation of the essential oil of Piper guineense from Cameroon shows sedative and anxiolytic-like effects in mice.},
  author={Joan Manjuh Tankam and Michiho Ito},
  journal={Biological & pharmaceutical bulletin},
  year={2013},
  volume={36 10},
  pages={1608-14}
}
The aromatherapeutical potential of Piper guineense essential oil was investigated in mice via inhalation administration, and the active compounds were identified. An open field test and light/dark transition test were used to evaluate the sedative and anxiolytic activities of this essential oil, respectively. P. guineense essential oil showed significant sedative activity at an effective dose of 4.0 × 10(-5) mg per cage compared to the control group. It also showed potent anxiolytic effect at… CONTINUE READING

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