Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice.

@article{Wiebelhaus2012InhalationET,
  title={Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice.},
  author={Jason M. Wiebelhaus and Justin L Poklis and Alphonse Poklis and Robert E. Vann and Aron H. Lichtman and Laura E. Wise},
  journal={Drug and alcohol dependence},
  year={2012},
  volume={126 3},
  pages={316-23}
}
BACKGROUND Use of synthetic "marijuana" has increased in recent years, produced adverse effects and prompted the temporary DEA ban of five specific cannabinoid analogs, including JWH-018. The objectives of the current study include determining the chemical content of the herbal product, Buzz, assessing its behavioral effects upon inhalation exposure to mice, determining whether CB(1) receptors mediate its pharmacological activity, and ascertaining its biodisposition in blood and various organs… CONTINUE READING
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