Inhalation Toxicity of Brevetoxin 3 in Rats Exposed for Twenty-Two Days

  title={Inhalation Toxicity of Brevetoxin 3 in Rats Exposed for Twenty-Two Days},
  author={Janet M. Benson and Fletcher F. Hahn and Thomas H. March and Jacob D Mcdonald and Andrea P. Gomez and Mohan J. Sopori and Andrea J. Bourdelais and Jerome P. Naar and Julia Zaias and Gregory D. Bossart and Daniel G. Baden},
  booktitle={Environmental health perspectives},
Brevetoxins are potent neurotoxins produced by the marine dinoflagellate Karenia brevis. Exposure to brevetoxins may occur during a K. brevis red tide when the compounds become aerosolized by wind and surf. This study assessed possible adverse health effects associated with inhalation exposure to brevetoxin 3, one of the major brevetoxins produced by K. brevis and present in aerosols collected along beaches affected by red tide. Male F344 rats were exposed to brevetoxin 3 at 0, 37, and 237… CONTINUE READING


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Florida ’ s red tide dinoflagellate Karina brevis may modulate its potency by producing a non - toxic competitive antagonist

  • AJ Bourdelais, S Campbell, J Benson, WM Abraham, J Naar, J Kubanek
  • 2003
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