Ingestion of castor oil plant seeds

@article{Aplin1997IngestionOC,
  title={Ingestion of castor oil plant seeds},
  author={Phil Aplin and Tony Eliseo},
  journal={Medical Journal of Australia},
  year={1997},
  volume={167}
}
  • P. AplinTony Eliseo
  • Published 1 September 1997
  • Environmental Science
  • Medical Journal of Australia
Ingestion of seeds of the castor oil plant is rare, and may cause toxicity but rarely death. The presumed toxic component is ricin, a highly potent cellular poison. We report the case of a young adult who ingested a large number of the seeds, causing initial toxicity, but with subsequent full recovery. The management of such ingestions and the apparent discrepancy between the extreme toxicity of ricin and the generally milder toxicity of ingested seeds are discussed. 

Hepatotoxicity from Castor Bean Ingestion in a Child

It seems prudent to follow for several days any patients who actually chewed castor beans before ingestion to see if they developed reversible hepatotoxicity beginning 48–72 hours after the ingestion ofCastor beans.

Ricin: Mechanism of Toxicity, Clinical Manifestations, and Vaccine Development. A Review

  • Leah G Doan
  • Biology, Medicine
    Journal of toxicology. Clinical toxicology
  • 2004
The mechanism of toxicity, major clinical manifestations, treatment, current methods of detection, and vaccine development are reviewed.

A Case of Accidental Ricin Poisoning

A case report of accidental, mild ricin poisoning by ingestion of ten Castor beans by a 70 year old man and a discussion about the toxicity of ricin, its use and misuse and the contrast between theoxicity of pure ricin and the ingestion of castor beans is discussed.

Toxicity of Ricin

The toxic dose in animals is low, although there is little toxicity data in humans, and most probable exposure in humans would be from inhalation of aerosols or mists containing ricin, or by ingestion.

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In this retrospective review, gastrointestinal symptoms were the most common symptoms described after reported exposures to castor bean seeds, and these exposures were not associated with serious morbidity, mortality, or delayed symptoms.

Handbook of Poisonous and Injurious Plants

A glossary ofBotanical Nomenclature and Glossary of Botanical Terms, including definitions ofPoisons, Poisoning Syndromes, and Their Clinical Management.

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Accidental and intended Ricinus communis intoxications in humans and animals have been known for centuries but the causative agent remained elusive until 1888 when Stillmark attributed the toxicity

Phytochemical and Biological Screening of Riccinus communis Seed Oil Grown Wild in Jammu & Kashmir

Investigation of the phyto-constituents present within the seed oil of Ricinus communis confirmed the presence of alkaloids, terpenoids, cardiac glycosides, tannins, steroids and saponins whereas flavonoids, anthraquinone and reducing sugars were found absent.

The Possible Protective Effect of Alpha-Lipoic Acid against Acute Ricin-Induced Nephrotoxicity in Adult Male Albino Rats

Rin produces oxidative nephrotoxic effects that markedly improved by the effective antioxidant properties of alpha lipoic acid, which is suggested to be used against ricin toxicity.

References

SHOWING 1-9 OF 9 REFERENCES

Castor bean toxicity re-examined: a new perspective.

The literature has been confused by recursive references among secondary sources and mortality statistics have been distorted by reliance on data generated nearly a century ago which do not accurately reflect the capabilities of modern medical management.

Modulation of ricin toxicity in mice by biologically active substances

The results demonstrate that the toxicity of ricin is modulated by a wide variety of structurally distinct chemicals and may involve different mechanisms, and the extent and direction of the modulation of ricIn toxicity is highly dependent upon pharmacokinetic variables, including dose and dosing interval.

Castor bean intoxication.

Ricin--a potent homicidal poison.

Poisoning by Castor-Oil Seeds

Plants - Toxalbumins ( Management / treatment protocol )

  • POISINOEX System