Ingestion and intracellular survival of Brucella abortus in human and bovine polymorphonuclear leukocytes.

@article{Riley1984IngestionAI,
  title={Ingestion and intracellular survival of Brucella abortus in human and bovine polymorphonuclear leukocytes.},
  author={Lela K. Riley and Donald C. Robertson},
  journal={Infection and immunity},
  year={1984},
  volume={46 1},
  pages={224-30}
}
Bovine polymorphonuclear leukocytes (PMNs) were found to be significantly more bactericidal than human PMNs against a smooth-intermediate strain of Brucella abortus (45/0), whereas there was no difference in bactericidal activity of the two kinds of PMNs against a rough strain of B. abortus (45/20). Electron microscopy of thin sections of PMNs revealed that both strains of B. abortus were readily ingested; however, the extent of degranulation was significantly less than in PMNs incubated with… CONTINUE READING
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