Ingested IFN-alpha preserves residual beta cell function in type 1 diabetes.

  title={Ingested IFN-alpha preserves residual beta cell function in type 1 diabetes.},
  author={Staley Armstrong Brod and Mark J. Atkinson and Victor R. Lavis and Patrick G. Brosnan and Dana Sue Hardin and Philip Orlander and Michael T. Nguyen and William Riley},
  journal={Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research},
  volume={21 12},
Type 1 diabetes mellitus is a chronic disorder that presumably results from an autoimmune destruction of the insulin-producing pancreatic beta cells. The therapeutic potential of interventions aimed at preventing type 1 diabetes can be assessed in newly diagnosed patients. Because there is a historical experience of a low incidence of spontaneous remission in type 1 diabetes mellitus, interventions preserving beta cell function have been used to identify positive therapeutic outcomes. We… CONTINUE READING