Ingenamine G and cyclostellettamines G-I, K, and L from the new Brazilian species of marine sponge Pachychalina sp.

@article{Oliveira2004IngenamineGA,
  title={Ingenamine G and cyclostellettamines G-I, K, and L from the new Brazilian species of marine sponge Pachychalina sp.},
  author={J de Oliveira and Achim Grube and Matthias K{\"o}ck and Roberto G S Berlinck and Mario L. Macedo and Ant{\'o}nio Ferreira and Eduardo Hajdu},
  journal={Journal of natural products},
  year={2004},
  volume={67 10},
  pages={
          1685-9
        }
}
  • J de Oliveira, Achim Grube, +4 authors Eduardo Hajdu
  • Published in Journal of natural products 2004
  • Biology, Medicine
  • The chemical investigation of the cytotoxic and antituberculosis active MeOH crude extract of the marine sponge Pachychalina sp. led to the isolation of six new nitrogenous metabolites, including ingenamine G (1), as well as a mixture of new cyclostellettamines G, H, I, K, and L (10-14) with the known cyclostellettamines A-F (4-9). Structural assignments of compound 1 were based on the analysis of MS and NMR data, while the structures of compounds 10-14 could be established by HPLC-MS/MS… CONTINUE READING

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