Infusion of hepatitis-B antibody in antigen-positive active chronic hepatitis.

@article{Reed1973InfusionOH,
  title={Infusion of hepatitis-B antibody in antigen-positive active chronic hepatitis.},
  author={William D. Reed and AdrianL. W. F. Eddleston and H. Cullens and Richard A. Williams and Arie Jeremy Zuckerman and Dr T. K. Peters and David Godfrey Williams and Willoughly Maycock},
  journal={Lancet},
  year={1973},
  volume={2 7842},
  pages={
          1347-51
        }
}
Abstract The effects of infusion of an immunoglobulin preparation with a high titre of antibody to hepatitis-B antigen (HBAg) have been investigated in six patients with active chronic hepatitis, in five of whom HBAg was persistently detected in the serum. The intravenous infusions were well tolerated and two patients only showed minor and transient evidence suggesting an immunecomplex reaction. Complexes containing HBAg were demonstrable after the infusion by electron microscopy in four cases… CONTINUE READING
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