Infusion of Mesenchymal Stem Cells Ameliorates Hyperglycemia in Type 2 Diabetic Rats

@inproceedings{Si2012InfusionOM,
  title={Infusion of Mesenchymal Stem Cells Ameliorates Hyperglycemia in Type 2 Diabetic Rats},
  author={Yiling Si and Yali Zhao and Haojie Hao and Jiejie Liu and Yelei Guo and Yiming Mu and Jing Shen and Yongmei Cheng and Xiaobing Fu and Weidong Han},
  booktitle={Diabetes},
  year={2012}
}
Infusion of mesenchymal stem cells (MSCs) has been shown to effectively lower blood glucose in diabetic individuals, but the mechanism involved could not be adequately explained by their potential role in promoting islet regeneration. We therefore hypothesized that infused MSCs might also contribute to amelioration of the insulin resistance of peripheral insulin target tissues. To test the hypothesis, we induced a diabetic rat model by high-fat diet/streptozotocin (STZ) administration… CONTINUE READING

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