Infused total nucleated cell dose is a better predictor of transplant outcomes than CD34+ cell number in reduced-intensity mobilized peripheral blood allogeneic hematopoietic cell transplantation.

@article{Martin2016InfusedTN,
  title={Infused total nucleated cell dose is a better predictor of transplant outcomes than CD34+ cell number in reduced-intensity mobilized peripheral blood allogeneic hematopoietic cell transplantation.},
  author={Paul S Martin and Shuli Li and Sarah Nikiforow and Edwin P Alyea and Joseph H Antin and Philippe F Armand and Corey S Cutler and Vincent Trien-Vinh Ho and Natasha Kekre and John Koreth and Chance John Luckey and Jerome Ritz and Robert J. Soiffer},
  journal={Haematologica},
  year={2016},
  volume={101 4},
  pages={499-505}
}
Mobilized peripheral blood is the most common graft source for allogeneic hematopoietic stem cell transplantation following reduced-intensity conditioning. In assessing the effect of donor cell dose and graft composition on major transplant outcomes in the reduced-intensity setting, prior studies focused primarily on CD34(+)cell dose and reported conflicting results, especially in relation to survival end-points. While the impact of total nucleated cell dose has been less frequently evaluated… CONTINUE READING
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