Infrequently methylated event at sites -181 to -9 within the 5' CpG island of E-cadherin in non-small cell lung cancer.

@article{Liu2009InfrequentlyME,
  title={Infrequently methylated event at sites -181 to -9 within the 5' CpG island of E-cadherin in non-small cell lung cancer.},
  author={Reng-Yun Liu and Zhe Lei and Wenwen Li and Linyan Xu and Zeyi Liu and Xiaofeng Chen and Jun Zhao and Hong-tao Zhang},
  journal={Experimental lung research},
  year={2009},
  volume={35 7},
  pages={541-53}
}
Epigenetic silencing of E-cadherin via aberrant methylation has been investigated in various human tumors, whereas evidence for elucidating mechanism underlying reduction of E-cadherin mRNA remains unclear in non-small cell lung cancer (NSCLC). The authors previously found that reduction of E-cadherin mRNA or protein expression has been frequently observed… CONTINUE READING